DARS2 antibody (AA 334-448)

Catalog No. ABIN7874036

This Rabbit Polyclonal antibody specifically detects DARS2 in WB, ELISA, ICC, IHC (p), IF and FACS. It exhibits reactivity toward Human.

Quick Overview for DARS2 antibody (AA 334-448) (ABIN7874036)

Target: DARS2 (Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DARS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-DARS2 Antibody

Binding Specificity: AA 334-448

Purpose: DARS2 Antibody

Purification: Antigen affinity purified

Immunogen: Amino acids D334-A448 from the human protein were used as the immunogen for the DARS2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DARS2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DARS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DARS2

Target: DARS2 (Aspartyl-tRNA Synthetase 2, Mitochondrial (DARS2))

Alternative Name: DARS2

Background: DARS2 contains conserved residues involved in ATP binding, tRNA binding, and aspartic acid recognition, as well as catalytic site motifs characteristic of amino acid tRNA synthetases. The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). The International Radiation Hybrid Mapping Consortium mapped the DARS2 gene to chromosome 1.

UniProt: Q6PI48