5HT1B Receptor antibody (AA 35-390)

Catalog No. ABIN7874165

This Rabbit Polyclonal antibody specifically detects 5HT1B Receptor in WB, ELISA, FACS and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for 5HT1B Receptor antibody (AA 35-390) (ABIN7874165)

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 5HT1B Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-5HT1B Receptor Antibody

Binding Specificity: AA 35-390

Purpose: 5HT1B Antibody / HTR1B

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids A35-S390) was used as the immunogen for the 5HT1B antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the 5HT1B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the 5HT1B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for 5HT1B Receptor

Target: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Alternative Name: 5HT1B

Background: 5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene. The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs.

UniProt: P28222

Pathways: JAK-STAT Signaling, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins