CD70 antibody (AA 36-191)

Catalog No. ABIN7874303

This Rabbit Polyclonal antibody specifically detects CD70 in WB, ELISA and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for CD70 antibody (AA 36-191) (ABIN7874303)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD70 Antibody

Binding Specificity: AA 36-191

Purpose: Cd70 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant mouse Cd70 protein (amino acids C36-Q191) was used as the immunogen for the Cd70 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cd70 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Cd70 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: Cd70

Background: CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

UniProt: O55237

Pathways: Cancer Immune Checkpoints