PRAM1 antibody (AA 361-670)

Catalog No. ABIN7874330

This Rabbit Polyclonal antibody specifically detects PRAM1 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for PRAM1 antibody (AA 361-670) (ABIN7874330)

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRAM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PRAM1 Antibody

Binding Specificity: AA 361-670

Purpose: PRAM1 Antibody / PML-RARA-regulated adapter molecule 1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E361-R670) was used as the immunogen for the PRAM1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PRAM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PRAM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PRAM1

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Alternative Name: PRAM1

Background: PML-RARA-regulated adapter molecule 1 is a protein that in humans is encoded by the PRAM1 gene. The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).

UniProt: Q96QH2

Pathways: Regulation of Leukocyte Mediated Immunity