PCCA antibody (AA 362-390)

Catalog No. ABIN7874333

This Rabbit Polyclonal antibody specifically detects PCCA in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PCCA antibody (AA 362-390) (ABIN7874333)

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PCCA Antibody

Binding Specificity: AA 362-390

Purpose: PCCA Antibody / Propionyl-CoA carboxylase alpha

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 362-390 from the human protein were used as the immunogen for the PCCA antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the PCCA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PCCA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PCCA

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Alternative Name: PCCA

Background: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P05165

Pathways: Monocarboxylic Acid Catabolic Process