TCF4 antibody (AA 365-671)

Catalog No. ABIN7874344

The Mouse Monoclonal anti-TCF4 antibody (Clone TCF4-1705) (ABIN7874344) specifically detects TCF4 in WB, ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TCF4 antibody (AA 365-671) (ABIN7874344)

Target: TCF4 (Transcription Factor 4 (TCF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TCF4-1705

Product Details anti-TCF4 Antibody

Binding Specificity: AA 365-671

Purpose: TCF4 Antibody

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 365-671 from the human protein was used as the immunogen for this TCF4 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the TCF4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the TCF4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4

Background: Recognizes a protein of 71 kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.

UniProt: P15884

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus