ENPP2 antibody (AA 377-406)

Catalog No. ABIN7874473

The Rabbit Polyclonal anti-ENPP2 antibody (ABIN7874473) specifically detects ENPP2 in WB and FACS. The antibody is reactive with Human samples.

Quick Overview for ENPP2 antibody (AA 377-406) (ABIN7874473)

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-ENPP2 Antibody

Binding Specificity: AA 377-406

Purpose: Autotaxin Antibody / ENPP2

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 377-406 from the human protein was used as the immunogen for the Autotaxin antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Autotaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Autotaxin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Alternative Name: Autotaxin

Background: ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form.

UniProt: Q13822