Glutathione Reductase antibody (AA 380-408)

Catalog No. ABIN7874518

The Rabbit Polyclonal anti-Glutathione Reductase antibody (ABIN7874518) specifically detects Glutathione Reductase in WB, IF, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Glutathione Reductase antibody (AA 380-408) (ABIN7874518)

Target: Glutathione Reductase (GSR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Reductase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Glutathione Reductase Antibody

Binding Specificity: AA 380-408

Purpose: GSR Antibody / Glutathione Reductase

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 380-408 from the human protein was used as the immunogen for the GSR antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the GSR antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the GSR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Glutathione Reductase

Target: Glutathione Reductase (GSR)

Alternative Name: GSR

Background: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis