LKB1 antibody (AA 393-420)

Catalog No. ABIN7874619

The Rabbit Polyclonal anti-LKB1 antibody is suitable to detect LKB1 in samples from Human and Mouse. It has been validated for WB, IF and IHC (p).

Quick Overview for LKB1 antibody (AA 393-420) (ABIN7874619)

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LKB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LKB1 Antibody

Binding Specificity: AA 393-420

Purpose: Stk11 Antibody / Liver kinase b1 / Lkb1

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 393-420 from the mouse protein was used as the immunogen for the Stk11 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Stk11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Stk11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LKB1

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Alternative Name: Stk11

Background: Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. [UniProt]

UniProt: Q9WTK7

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect