Glutaminase antibody (AA 396-654)

Catalog No. ABIN7874647

The Rabbit Polyclonal anti-Glutaminase antibody (ABIN7874647) specifically detects Glutaminase in WB, ELISA, IF, FACS and IHC (p). The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for Glutaminase antibody (AA 396-654) (ABIN7874647)

Target: Glutaminase (GLS)

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaminase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Glutaminase Antibody

Binding Specificity: AA 396-654

Purpose: GLS Antibody / Glutaminase

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids K396-N654) was used as the immunogen for the GLS antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GLS antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GLS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Glutaminase

Target: Glutaminase (GLS)

Alternative Name: GLS

Background: This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.

UniProt: O94925

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effect