PHF15 antibody (AA 397-746)

Catalog No. ABIN7874652

The Rabbit Polyclonal anti-PHF15 antibody is suitable to detect PHF15 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for PHF15 antibody (AA 397-746) (ABIN7874652)

Target: PHF15 (PHD Finger Protein 15 (PHF15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PHF15 Antibody

Binding Specificity: AA 397-746

Purpose: JADE2 Antibody / PHF15

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids L397-D746) was used as the immunogen for the JADE2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the JADE2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the JADE2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PHF15

Target: PHF15 (PHD Finger Protein 15 (PHF15))

Alternative Name: JADE2

Background: PHF15, also known as Protein Jade-2, has 3 isoforms, a 790 amino acid isoform that is 87 kDa, a 789 amino acid isoform that is 87 kDa and a 562 amino acid isoform that is 63 kDa, has a histone H4-specific acetyltransferase activity as a component of the HBO1complex, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. This protein has been shown an interaction with ING4, KAT7, ING5, PACSIN, ZBTB3, ZBTB5, ZNF496, and VHL proteins in histone H3 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, and histone H4-K12 acetylation biological processes.

UniProt: Q9NQC1