Histone H2A antibody (AA 4-121)

Catalog No. ABIN7874656

The Rabbit Polyclonal anti-Histone H2A antibody (ABIN7874656) specifically detects Histone H2A in WB and IHC (p). The antibody is reactive with Zebrafish (Danio rerio) samples.

Quick Overview for Histone H2A antibody (AA 4-121) (ABIN7874656)

Target: Histone H2A

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Histone H2A Antibody

Binding Specificity: AA 4-121

Purpose: Zebrafish H2ax Antibody / Histone H2A.X

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Histone H2A.X/H2AFX recombinant protein (amino acids R4-T121) was used as the immunogen for the Zebrafish H2ax antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish H2ax antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish H2ax antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Histone H2A

Target: Histone H2A

Background: H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

UniProt: Q7ZUY3