MED17 antibody (AA 4-561)

Catalog No. ABIN7874682

The Rabbit Polyclonal anti-MED17 antibody is suitable to detect MED17 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for MED17 antibody (AA 4-561) (ABIN7874682)

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-MED17 Antibody

Binding Specificity: AA 4-561

Purpose: MED17 Antibody / Trap80 / ARC77

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (V4-E561) was used as the immunogen for the MED17 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MED17 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MED17 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Alternative Name: MED17

Background: Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha