HNRNPK antibody (AA 40-463)

Catalog No. ABIN7874702

This Rabbit Polyclonal antibody specifically detects HNRNPK in WB, ELISA, IF and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HNRNPK antibody (AA 40-463) (ABIN7874702)

Target: HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-HNRNPK Antibody

Binding Specificity: AA 40-463

Purpose: hnRNP K Antibody / HNRNPK / TUNP

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D40-F463) was used as the immunogen for the hnRNP K antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the hnRNP K antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the hnRNP K antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HNRNPK

Target: HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

Alternative Name: hnRNP K

Background: Heterogeneous nuclear ribonucleoprotein K, also called Transformation up-regulated nuclear protein (TUNP), is a protein that in humans is encoded by the HNRNPK gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progression. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.

UniProt: P61978