PCCA antibody (AA 403-728)

Catalog No. ABIN7874806

The Rabbit Polyclonal anti-PCCA antibody (ABIN7874806) specifically detects PCCA in WB, ELISA, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PCCA antibody (AA 403-728) (ABIN7874806)

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-PCCA Antibody

Binding Specificity: AA 403-728

Purpose: PCCA Antibody / Propionyl-CoA carboxylase alpha

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids E403-E728) was used as the immunogen for the PCCA antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PCCA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PCCA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PCCA

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Alternative Name: PCCA

Background: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P05165

Pathways: Monocarboxylic Acid Catabolic Process