Angiopoietin 2 antibody (AA 404-432)

Catalog No. ABIN7874807

This Rabbit Polyclonal antibody specifically detects Angiopoietin 2 in WB, IHC (p) and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for Angiopoietin 2 antibody (AA 404-432) (ABIN7874807)

Target: Angiopoietin 2 (ANGPT2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiopoietin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-Angiopoietin 2 Antibody

Binding Specificity: AA 404-432

Purpose: Angiopoietin 2 Antibody / ANG2 / ANGPT2

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 404-432 from the human protein was used as the immunogen for the Angiopoietin 2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Angiopoietin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Angiopoietin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Angiopoietin 2

Target: Angiopoietin 2 (ANGPT2)

Alternative Name: Angiopoietin 2

Background: The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

UniProt: O15123

Pathways: RTK Signaling