ADAM8 antibody (AA 41-290)

Catalog No. ABIN7874834

This Rabbit Polyclonal antibody specifically detects ADAM8 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for ADAM8 antibody (AA 41-290) (ABIN7874834)

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-ADAM8 Antibody

Binding Specificity: AA 41-290

Purpose: ADAM8 Antibody / MS2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R41-L290) was used as the immunogen for the ADAM8 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ADAM8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ADAM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ADAM8

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Alternative Name: ADAM8

Background: A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

UniProt: P78325

Pathways: Activation of Innate immune Response, M Phase