EHD2 antibody (AA 415-449)

Catalog No. ABIN7874883

The Rabbit Polyclonal anti-EHD2 antibody is suitable to detect EHD2 in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for EHD2 antibody (AA 415-449) (ABIN7874883)

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-EHD2 Antibody

Binding Specificity: AA 415-449

Purpose: EHD2 Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 415-449 from the human protein was used as the immunogen for the EHD2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the EHD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the EHD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for EHD2

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Alternative Name: EHD2

Background: EH domain-containing protein 2 plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Required for translocation of FER1L5 to the plasma membrane. Binds ATP, does not bind GTP (By similarity).

UniProt: Q9NZN4

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development