FGG antibody (AA 420-449)
Quick Overview for FGG antibody (AA 420-449) (ABIN7874931)
Target
See all FGG AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 420-449
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Purpose
- FGG Antibody / Fibrinogen gamma chain / FIBG
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Purification
- Purified
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Immunogen
- A portion of amino acids 420-449 from the human protein was used as the immunogen for the FGG antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the FGG antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the FGG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FGG (Fibrinogen gamma Chain (FGG))
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Alternative Name
- FGG
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Background
- FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.
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UniProt
- P02679
Target
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