DNMT3L antibody (AA 43-421)

Catalog No. ABIN7874969

This Rabbit Polyclonal antibody specifically detects DNMT3L in WB, ELISA and FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for DNMT3L antibody (AA 43-421) (ABIN7874969)

Target: DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNMT3L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-DNMT3L Antibody

Binding Specificity: AA 43-421

Purpose: Dnmt3l Antibody

Purification: Affinity purified

Immunogen: An E. coli-derived mouse protein (amino acids A43-L421) was used as the immunogen for the Dnmt3l antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Dnmt3l antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Dnmt3l antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DNMT3L

Target: DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Alternative Name: Dnmt3l

Background: DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9CWR8