ICAM5 antibody (AA 430-682)

Catalog No. ABIN7874979

The Rabbit Polyclonal anti-ICAM5 antibody is suitable to detect ICAM5 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for ICAM5 antibody (AA 430-682) (ABIN7874979)

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-ICAM5 Antibody

Binding Specificity: AA 430-682

Purpose: ICAM5 Antibody / Intercellular adhesion molecule 5

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids R430-G682) was used as the immunogen for the ICAM5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ICAM5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ICAM5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ICAM5

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Alternative Name: ICAM5

Background: Intercellular adhesion molecule 5 is a protein that in humans is encoded by the ICAM5 gene. The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

UniProt: Q9UMF0

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location