INSM2 antibody (AA 432-540)

Catalog No. ABIN7874981

This Mouse Monoclonal antibody specifically detects INSM2 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for INSM2 antibody (AA 432-540) (ABIN7874981)

Target: INSM2 (Insulinoma-Associated 2 (INSM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This INSM2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: INSM2-4291

Product Details anti-INSM2 Antibody

Binding Specificity: AA 432-540

Purpose: INSM2 Antibody / Insulinoma Associated 2

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 432-540 from the human protein was used as the immunogen for the INSM2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the INSM2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the INSM2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for INSM2

Target: INSM2 (Insulinoma-Associated 2 (INSM2))

Alternative Name: INSM2

Background: IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.

UniProt: Q96T92