HBS1L antibody (AA 460-486)

Catalog No. ABIN7875126

The Rabbit Polyclonal anti-HBS1L antibody is suitable to detect HBS1L in samples from Human and Mouse. It has been validated for WB.

Quick Overview for HBS1L antibody (AA 460-486) (ABIN7875126)

Target: HBS1L (HBS1-Like (HBS1L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBS1L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HBS1L Antibody

Binding Specificity: AA 460-486

Purpose: HBS1L Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 460-486 from the human protein was used as the immunogen for the HBS1L antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the HBS1L antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HBS1L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HBS1L

Target: HBS1L (HBS1-Like (HBS1L))

Alternative Name: HBS1L

Background: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

UniProt: Q9Y450