alpha 2 Antiplasmin antibody (AA 461-491)

Catalog No. ABIN7875133

The Rabbit Polyclonal anti-alpha 2 Antiplasmin antibody (ABIN7875133) specifically detects alpha 2 Antiplasmin in WB, ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for alpha 2 Antiplasmin antibody (AA 461-491) (ABIN7875133)

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 2 Antiplasmin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-alpha 2 Antiplasmin Antibody

Binding Specificity: AA 461-491

Purpose: SERPINF2 Antibody / Alpha-2-Antiplasmin

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K461-K491) was used as the immunogen for the SERPINF2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SERPINF2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SERPINF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for alpha 2 Antiplasmin

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Alternative Name: SERPINF2

Background: Alpha 2-antiplasmin (or a2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin. Plasmin is an important enzyme that participates in fibrinolysis and degradation of various other proteins. This protein is encoded by the SERPINF2 gene. This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P08697

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones