HAO1 antibody (AA 48-370)

Catalog No. ABIN7875207

The Rabbit Polyclonal anti-HAO1 antibody is suitable to detect HAO1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC (p) and FACS.

Quick Overview for HAO1 antibody (AA 48-370) (ABIN7875207)

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-HAO1 Antibody

Binding Specificity: AA 48-370

Purpose: Hydroxyacid oxidase 1 Antibody / HAO1

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids K48-I370) was used as the immunogen for the Hydroxyacid oxidase 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Hydroxyacid oxidase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Hydroxyacid oxidase 1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HAO1

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Alternative Name: Hydroxyacid oxidase 1

Background: Hydroxyacid oxidase (glycolate oxidase) 1 is a protein that in humans is encoded by the HAO1 gene. This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.

UniProt: Q9UJM8

Pathways: Monocarboxylic Acid Catabolic Process