ITK antibody (AA 49-465)

Catalog No. ABIN7875257

This Rabbit Polyclonal antibody specifically detects ITK in WB, ELISA, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ITK antibody (AA 49-465) (ABIN7875257)

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITK Antibody

Binding Specificity: AA 49-465

Purpose: IL2-inducible T-cell kinase Antibody / ITK

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R49-F465) was used as the immunogen for the IL2-inducible T-cell kinase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IL2-inducible T-cell kinase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IL2-inducible T-cell kinase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ITK

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Alternative Name: IL2-inducible T-cell kinase

Background: Tyrosine-protein kinase ITK/TSK, also known as interleukin-2-inducible T-cell kinase or simply ITK, is a protein that in humans is encoded by the ITK gene. It is a member of the TEC family of kinases. This gene is mapped to 5q33.3. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein is thought to play a role in T-cell proliferation and differentiation. Furthermore, ITK is functionally important for the development and effector function of Th2 and Th17 cells.

UniProt: Q08881

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway