DNM2 antibody (AA 498-785)

Catalog No. ABIN7875283

The Rabbit Polyclonal anti-DNM2 antibody (ABIN7875283) specifically detects DNM2 in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for DNM2 antibody (AA 498-785) (ABIN7875283)

Target: DNM2 (Dynamin 2 (DNM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-DNM2 Antibody

Binding Specificity: AA 498-785

Purpose: DNM2 Antibody / Dynamin 2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids N498-R785) was used as the immunogen for the DNM2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DNM2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DNM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DNM2

Target: DNM2 (Dynamin 2 (DNM2))

Alternative Name: DNM2

Background: Dynamin-2 is a protein that in humans is encoded by the DNM2 gene. Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

UniProt: P50570

Pathways: Toll-Like Receptors Cascades