Caveolin 3 antibody (AA 5-31)
Quick Overview for Caveolin 3 antibody (AA 5-31) (ABIN7875302)
Target
See all Caveolin 3 (CAV3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 5-31
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Purpose
- Caveolin-3 Antibody / CAV3
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Purification
- Purified
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Immunogen
- A portion of amino acids 5-31 from the human protein was used as the immunogen for the Caveolin-3 antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the Caveolin-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Caveolin-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Caveolin 3 (CAV3)
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Alternative Name
- Caveolin-3
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Background
- CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in its gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD).
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UniProt
- P56539
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Pathways
- Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
Target
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