CD207 antibody (AA 50-250)

Catalog No. ABIN7875350

This Mouse Monoclonal antibody specifically detects CD207 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD207 antibody (AA 50-250) (ABIN7875350)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD207 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: LGRN-7428

Product Details anti-CD207 Antibody

Binding Specificity: AA 50-250

Purpose: CD207 Antibody / Langerin (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the CD207 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CD207 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CD207 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: CD207

Background: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

UniProt: Q9UJ71