Fatty Acid Synthase antibody (AA 508-2511)

Catalog No. ABIN7875502

The Rabbit Polyclonal anti-Fatty Acid Synthase antibody (ABIN7875502) specifically detects Fatty Acid Synthase in WB and IHC (p). The antibody is reactive with Zebrafish (Danio rerio) samples.

Quick Overview for Fatty Acid Synthase antibody (AA 508-2511) (ABIN7875502)

Target: Fatty Acid Synthase (FASN)

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Fatty Acid Synthase Antibody

Binding Specificity: AA 508-2511

Purpose: Zebrafish Fasn Antibody / Fatty acid synthase / Fas

Purification: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Fasn recombinant protein (amino acids Q508-G2511) was used as the immunogen for the Zebrafish Fasn antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Fasn antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Fasn antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: Fasn

Background: Fatty acid synthase, also called Fas and Fasn, is a large multi enzyme protein complex that catalyzes the synthesis of long chain saturated fatty acids from acetyl coenzyme A and malonyl coenzyme A in the presence of nicotinamide adenine dinucleotide phosphate. In zebrafish, fatty acid synthase is essential for lipid metabolism and plays a central role in energy storage, membrane formation, and signaling pathways during development and growth.

Fatty acid synthase is highly expressed in metabolically active tissues such as the liver, brain, and developing embryos. It supports rapid cell division and tissue expansion by supplying fatty acids needed for phospholipid and triglyceride production. In zebrafish embryos, the expression of fatty acid synthase begins early and is critical for proper organogenesis and survival.

Altered regulation of fatty acid synthase is associated with metabolic disorders, cancer, and developmental abnormalities. Due to its evolutionary conservation and functional importance, zebrafish fatty acid synthase is widely used as a model to study lipid biosynthesis, energy metabolism, and the effects of dietary and environmental factors on fat production. It is also a valuable target for screening compounds that modulate lipogenesis or impact metabolic health.

UniProt: E7F5V3

Pathways: AMPK Signaling