Netrin 3 antibody (AA 51-473)
This Rabbit Polyclonal antibody specifically detects Netrin 3 in WB, ELISA, IHC (p) and IF. It exhibits reactivity toward Human and Rat.
Catalog No. ABIN7875521
$625.62
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Netrin 3 antibody (AA 51-473) (ABIN7875521)
Target
See all Netrin 3 (Ntn3) Antibodies
Netrin 3 (Ntn3)
Reactivity
Human, Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
This Netrin 3 antibody is un-conjugated
Application
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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Binding Specificity
- AA 51-473
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Purpose
- NTN3 Antibody / Netrin 3
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Purification
- Antigen affinity purified
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Immunogen
- An E.coli-derived human recombinant protein (R51-R473) was used as the immunogen for the NTN3 antibody.
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Isotype
- IgG
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anti-Netrin 3 (Ntn3) (AA 445-458), (Secreted) antibody
Ntn3 Reactivity: Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal dilution of the NTN3 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the NTN3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Netrin 3 (Ntn3)
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Alternative Name
- NTN3
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Background
- Netrins are a family of highly conserved proteins responsible for axon guidance and cell movement throughout neural development. Netrins can be divided into secreted netrins (netrin 1,3,4 and 5) and membrane-tethered glycophosphatidylinositol (GPI)-linked netrins (netrin G1 and G2). Secreted netrins carry their function via interaction with several receptors that include the deleted in colorectal (DCC) family, and the uncoordinated-5 (UNC5-A through UNC5-D) family. Netrin-3 was discovered in 1997 using sequence homology searching of netrin-2. Similarly to other netrins, Netrin-3 plays an important role in the development of the nervous system. Netrin-3 structure consist of a laminin-like domain located on the N-terminal, three epidermal growth factors like repeats (EGF), and a C-terminal netrin-like domain (NTR). Mutations in NTN3, the gene encoding netrin-3 was found to be associated with the development of several carcinomas.
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UniProt
- O00634
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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