ERN2 antibody (AA 517-919)

Catalog No. ABIN7875536

This Rabbit Polyclonal antibody specifically detects ERN2 in ELISA, WB and FACS. It exhibits reactivity toward Human.

Quick Overview for ERN2 antibody (AA 517-919) (ABIN7875536)

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERN2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-ERN2 Antibody

Binding Specificity: AA 517-919

Purpose: IRE2 Antibody / ERN2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K517-P919) was used as the immunogen for the IRE2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IRE2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IRE2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ERN2

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Alternative Name: IRE2

Background: IRE2/ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of IRE2/ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.

UniProt: Q76MJ5