TdT antibody (AA 52-192)

Catalog No. ABIN7875552

The Mouse Monoclonal anti-TdT antibody is suitable to detect TdT in samples from Human. It has been validated for ELISA and IHC (p).

Quick Overview for TdT antibody (AA 52-192) (ABIN7875552)

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TdT antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DNTT-1453

Product Details anti-TdT Antibody

Binding Specificity: AA 52-192

Purpose: TdT Antibody / DNA nucleotidylexotransferase

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 52-192 from the human protein was used as the immunogen for the TdT antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the TdT antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the TdT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for TdT

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Alternative Name: TdT

Background: Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3 termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. TdT is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.

UniProt: P04053

Pathways: DNA Damage Repair