DYRK2 antibody (AA 521-549)
Quick Overview for DYRK2 antibody (AA 521-549) (ABIN7875581)
Target
See all DYRK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 521-549
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Purpose
- DYRK2 Antibody
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 521-549 from the mouse protein was used as the immunogen for the DYRK2 antibody.
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Isotype
- Ig Fraction
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anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 105-135), (N-Term) antibody
DYRK2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB3008 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 521-549), (C-Term) antibodyDYRK2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB34467 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 6E2 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2F9 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4G11 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2F9 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 502-601) antibodyDYRK2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) antibodyDYRK2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 105-135) antibodyDYRK2 Reactivity: Human WB Host: Mouse Monoclonal 492CT4-2-4 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) antibodyDYRK2 Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the DYRK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the DYRK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
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Alternative Name
- DYRK2
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Background
- Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
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UniProt
- Q5U4C9
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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