Glutaminase antibody (AA 53-312)
Quick Overview for Glutaminase antibody (AA 53-312) (ABIN7875595)
Target
See all Glutaminase (GLS) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 53-312
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Purpose
- Zebrafish Gls Antibody / Glutaminase / Isoforms a & b
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Purification
- Antigen affinity chromatography
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Immunogen
- An E.coli-derived zebrafish Glsa/b recombinant protein (amino acids K53-S312) was used as the immunogen for the Zebrafish Gls antibody. This antibody will detect the a and b isoforms.
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Isotype
- Ig Fraction
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Application Notes
- Optimal dilution of the Zebrafish Gls antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the Zebrafish Gls antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Glutaminase (GLS)
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Alternative Name
- Gls
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Background
- This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.
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Pathways
- Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effect
Target
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