Recombinant Frataxin antibody (AA 57-210)

Catalog No. ABIN7875800

This Mouse Monoclonal antibody specifically detects Frataxin in ELISA. It exhibits reactivity toward Human.

Quick Overview for Recombinant Frataxin antibody (AA 57-210) (ABIN7875800)

Target: Frataxin (FXN)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Frataxin antibody is un-conjugated

Application: ELISA

Grade: Carrier-free

Clone: RFXN-2124

Product Details anti-Frataxin Antibody

Binding Specificity: AA 57-210

Purpose: Recombinant Frataxin Antibody / FXN (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Frataxin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Frataxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Frataxin

Target: Frataxin (FXN)

Alternative Name: Frataxin

Background: Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size