TYK2 antibody (AA 581-719)

Catalog No. ABIN7875863

This Rabbit Polyclonal antibody specifically detects TYK2 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for TYK2 antibody (AA 581-719) (ABIN7875863)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TYK2 Antibody

Binding Specificity: AA 581-719

Purpose: TYK2 Antibody / Non-receptor tyrosine-protein kinase TYK2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids F581-A719) was used as the immunogen for the TYK2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TYK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TYK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Alternative Name: TYK2

Background: Non-receptor tyrosine-protein kinase TYK2 is an enzyme that in humans is encoded by the TYK2 gene. This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35.

UniProt: P29597

Pathways: JAK-STAT Signaling, Hepatitis C