Calretinin antibody (AA 59-90)

Catalog No. ABIN7875915

The Rabbit Polyclonal anti-Calretinin antibody is suitable to detect Calretinin in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC (p), IF and FACS.

Quick Overview for Calretinin antibody (AA 59-90) (ABIN7875915)

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calretinin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-Calretinin Antibody

Binding Specificity: AA 59-90

Purpose: Calbindin 2 Antibody / CALB2 / Calretinin

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids S59-Q90) was used as the immunogen for the Calbindin 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Calbindin 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Calbindin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Alternative Name: Calbindin 2

Background: Calretinin, also known as calbindin 2 (formerly 29 kDa calbindin), is a calcium-binding protein involved in calcium signaling. In humans, the calretinin protein is encoded by the CALB2 gene. It is mapped to 16q22.2. This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.

UniProt: P22676