APOB antibody (AA 592-689)

Catalog No. ABIN7875919

The Mouse Monoclonal anti-APOB antibody (Clone APOB-4335) (ABIN7875919) specifically detects APOB in IHC (p). The antibody is reactive with Human samples.

Quick Overview for APOB antibody (AA 592-689) (ABIN7875919)

Target: APOB (Apolipoprotein B (APOB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOB antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: APOB-4335

Product Details anti-APOB Antibody

Binding Specificity: AA 592-689

Purpose: APOB Antibody / Apolipoprotein B (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A portin of amino acids 592-689 from the human protein was used as the immunogen for the Apolipoprotein B antibody.

Isotype: IgG2b, IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the Apolipoprotein B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Apolipoprotein B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for APOB

Target: APOB (Apolipoprotein B (APOB))

Alternative Name: APOB

Background: Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by APOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene.

UniProt: P04114

Pathways: Lipid Metabolism