Recombinant Villin 1 antibody (AA 600-700)

Catalog No. ABIN7876019

This Mouse Monoclonal antibody specifically detects Villin 1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Villin 1 antibody (AA 600-700) (ABIN7876019)

Target: Villin 1 (VIL1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Villin 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RVIL1-8336

Product Details anti-Villin 1 Antibody

Binding Specificity: AA 600-700

Purpose: VIL1 Antibody / Villin

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 600-700) from the human protein was used as the immunogen for the VIL1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the VIL1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the VIL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Villin 1

Target: Villin 1 (VIL1)

Alternative Name: VIL1

Background: Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization