DLL4 antibody (AA 608-641)

Catalog No. ABIN7876104

The Rabbit Polyclonal anti-DLL4 antibody is suitable to detect DLL4 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for DLL4 antibody (AA 608-641) (ABIN7876104)

Target: DLL4 (delta-Like 4 (DLL4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLL4 Antibody

Binding Specificity: AA 608-641

Purpose: DLL4 Antibody (C-Terminal Region)

Purification: Antigen affinity

Immunogen: A portion of amino acids 608-641 from human DLL4 was used as the immunogen for the DLL4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the DLL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the DLL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4

Background: Delta-like protein 4 is involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. [UniProt]

UniProt: Q9NR61

Pathways: Notch Signaling