TRMT1 antibody (AA 61-626)

Catalog No. ABIN7876112

This Rabbit Polyclonal antibody specifically detects TRMT1 in WB, ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for TRMT1 antibody (AA 61-626) (ABIN7876112)

Target: TRMT1 (tRNA Methyltransferase 1 (TRMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-TRMT1 Antibody

Binding Specificity: AA 61-626

Purpose: TRMT1 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A61-P626) was used as the immunogen for the TRMT1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TRMT1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TRMT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TRMT1

Target: TRMT1 (tRNA Methyltransferase 1 (TRMT1))

Alternative Name: TRMT1

Background: This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome.

UniProt: Q9NXH9

Pathways: SARS-CoV-2 Protein Interactome