MVD antibody (AA 62-374)

Catalog No. ABIN7876162

The Rabbit Polyclonal anti-MVD antibody (ABIN7876162) specifically detects MVD in WB, ELISA, IHC (p) and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for MVD antibody (AA 62-374) (ABIN7876162)

Target: MVD (Mevalonate (Diphospho) Decarboxylase (MVD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-MVD Antibody

Binding Specificity: AA 62-374

Purpose: Diphosphomevalonate decarboxylase Antibody / MVD

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids E62-Q374) was used as the immunogen for the Diphosphomevalonate decarboxylase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Diphosphomevalonate decarboxylase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Diphosphomevalonate decarboxylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MVD

Target: MVD (Mevalonate (Diphospho) Decarboxylase (MVD))

Alternative Name: Diphosphomevalonate decarboxylase

Background: The enzyme mevalonate pyrophosphate decarboxylase (MVD, EC 4.1.1.33) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate. This unusual enzyme decarboxylates and dehydrates its substrate while hydrolyzing ATP. As a unique enzyme in one of the early steps in cholesterol biosynthesis, MVD may be a useful target for drugs aimed at lowering serum cholesterol levels. This gene is mapped to chromosome 16q24.3 based on an alignment of the MVD sequence.

UniProt: P53602