TLR1 antibody (AA 62-404)

Catalog No. ABIN7876164

The Rabbit Polyclonal anti-TLR1 antibody is suitable to detect TLR1 in samples from Human and Rat. It has been validated for WB, FACS, ELISA and IHC (p).

Quick Overview for TLR1 antibody (AA 62-404) (ABIN7876164)

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TLR1 Antibody

Binding Specificity: AA 62-404

Purpose: Toll-like Receptor 1 Antibody / TLR1

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids T62-D404) was used as the immunogen for the Toll-like Receptor 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Toll-like Receptor 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Toll-like Receptor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Alternative Name: Toll-like Receptor 1

Background: Toll-like receptor 1 (TLR1), also called TIL or CD281 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

UniProt: Q15399

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades