LARS antibody (AA 628-855)

Catalog No. ABIN7876202

This Rabbit Polyclonal antibody specifically detects LARS in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LARS antibody (AA 628-855) (ABIN7876202)

Target: LARS (Leucyl-tRNA Synthetase (LARS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LARS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LARS Antibody

Binding Specificity: AA 628-855

Purpose: Leucyl tRNA synthetase Antibody / LARS

Purification: Antigen affinity purified

Immunogen: Amino acids Q628-Q855 from the human protein were used as the immunogen for the Leucyl tRNA synthetase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Leucyl tRNA synthetase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Leucyl tRNA synthetase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LARS

Target: LARS (Leucyl-tRNA Synthetase (LARS))

Alternative Name: Leucyl tRNA synthetase

Background: Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene. This gene is mapped to 5q32. It encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed.

UniProt: Q9P2J5

Pathways: EGFR Signaling Pathway