The Rabbit Polyclonal anti-PIGR antibody (ABIN7876267) specifically detects PIGR in WB, IHC (p), IF and FACS.
The antibody is reactive with Human samples.
The stated application concentrations are suggested starting points. Titration of the PIGR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the PIGR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
PIGR
(Polymeric Immunoglobulin Receptor (PIGR))
Alternative Name
PIGR
Background
PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.