TLR6 antibody (AA 65-553)

Catalog No. ABIN7876282

The Rabbit Polyclonal anti-TLR6 antibody (ABIN7876282) specifically detects TLR6 in WB, ELISA and FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for TLR6 antibody (AA 65-553) (ABIN7876282)

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TLR6 Antibody

Binding Specificity: AA 65-553

Purpose: Tlr6 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant mouse protein (amino acids S65-E553) was used as the immunogen for the Tlr6 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Tlr6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Tlr6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TLR6

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Alternative Name: Tlr6

Background: Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.

UniProt: Q9EPW9

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades