FAP antibody (AA 65-580)

Catalog No. ABIN7876283

This Rabbit Polyclonal antibody specifically detects FAP in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for FAP antibody (AA 65-580) (ABIN7876283)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-FAP Antibody

Binding Specificity: AA 65-580

Purpose: Fibroblast activation protein alpha Antibody / FAP

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q65-Q580) was used as the immunogen for the Fibroblast activation protein alpha antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Fibroblast activation protein alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Fibroblast activation protein alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Alternative Name: Fibroblast activation protein alpha

Background: Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that in humans is encoded by the FAP gene. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q12884

Pathways: Tube Formation