HS2ST1 antibody (AA 68-354)

Catalog No. ABIN7876400

This Rabbit Polyclonal antibody specifically detects HS2ST1 in IHC (p). It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for HS2ST1 antibody (AA 68-354) (ABIN7876400)

Target: HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS2ST1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HS2ST1 Antibody

Binding Specificity: AA 68-354

Purpose: Zebrafish Hs2st1 Antibody / Hs2st1a / Hs2st1b

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Hs2st1a/b recombinant protein (amino acids E68-N354) was used as the immunogen for the Zebrafish Hs2st1 antibody. This antibody will detect both the a and b isoforms.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Hs2st1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Hs2st1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HS2ST1

Target: HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))

Alternative Name: Hs2st1

Background: Heparan sulfate 2-O-sulfotransferase 1 is an enzyme that in humans is encoded by the HS2ST1 gene. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.

UniProt: A1L1P8

Pathways: Glycosaminoglycan Metabolic Process, Tube Formation, SARS-CoV-2 Protein Interactome