Adrenomedullin antibody (AA 69-96)

Catalog No. ABIN7876453

The Rabbit Polyclonal anti-Adrenomedullin antibody (ABIN7876453) specifically detects Adrenomedullin in WB and FACS. The antibody is reactive with Human samples.

Quick Overview for Adrenomedullin antibody (AA 69-96) (ABIN7876453)

Target: Adrenomedullin (ADM)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adrenomedullin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Adrenomedullin Antibody

Binding Specificity: AA 69-96

Purpose: Adrenomedullin antibody / ADM

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 69-96 from the human protein was used as the immunogen for the Adrenomedullin antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Adrenomedullin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Adrenomedullin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Adrenomedullin

Target: Adrenomedullin (ADM)

Alternative Name: Adrenomedullin

Target Type: Hormone

Background: ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation